Olfactory receptor 2A1/2A42 (OR2A1)
Homo sapiens — UniProt Q8NGT9
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 2A1/2A42 (OR2A1) is a protein from Homo sapiens identified by UniProt accession Q8NGT9, 310 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8NGT9; gene symbol OR2A1.
- Organism: Homo sapiens.
- Length: 310 amino acids.
- Top disease associations (Open Targets): genetic disorder, diffuse large B-cell lymphoma and actinic keratosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 2A1/2A42 |
|---|---|
| UniProt accession | Q8NGT9 |
| Gene | OR2A1 |
| Organism | Homo sapiens |
| Length | 310 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.12
- diffuse large B-cell lymphoma · score 0.07
- actinic keratosis · score 0.04
- neoplasm · score 0.01
- pulmonary hypertension · score 0.01
- reading · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGT9-F1 | alphafold | PREDICTED | 86.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGT9.
Amino-acid sequence (310 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR2A1?
The strongest Open Targets associations for OR2A1 are genetic disorder, diffuse large B-cell lymphoma, actinic keratosis, neoplasm and pulmonary hypertension.
How long is the OR2A1 protein?
The Homo sapiens OR2A1 protein (UniProt Q8NGT9) is 310 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGT9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGT9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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