Probable G-protein coupled receptor 150 (GPR150)
Homo sapiens — UniProt Q8NGU9
Data last refreshed: (UniProt release unknown)
Key facts
Probable G-protein coupled receptor 150 (GPR150) is a protein from Homo sapiens identified by UniProt accession Q8NGU9, 434 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q8NGU9; gene symbol GPR150.
- Organism: Homo sapiens.
- Length: 434 amino acids.
- Top disease associations (Open Targets): Arrhythmogenic right ventricular dysplasia, Brugada syndrome and familial atrial fibrillation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable G-protein coupled receptor 150 |
|---|---|
| UniProt accession | Q8NGU9 |
| Gene | GPR150 |
| Organism | Homo sapiens |
| Length | 434 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- Arrhythmogenic right ventricular dysplasia · score 0.06
- Brugada syndrome · score 0.06
- familial atrial fibrillation · score 0.06
- Familial progressive cardiac conduction defect · score 0.06
- Romano-Ward syndrome · score 0.06
- Familial short QT syndrome · score 0.05
- Wolff-Parkinson-White Syndrome · score 0.05
- dilated cardiomyopathy · score 0.05
- familial sick sinus syndrome · score 0.04
- arrhythmogenic right ventricular dysplasia 12 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGU9-F1 | alphafold | PREDICTED | 70.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGU9.
Amino-acid sequence (434 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPR150?
The strongest Open Targets associations for GPR150 are Arrhythmogenic right ventricular dysplasia, Brugada syndrome, familial atrial fibrillation, Familial progressive cardiac conduction defect and Romano-Ward syndrome.
How long is the GPR150 protein?
The Homo sapiens GPR150 protein (UniProt Q8NGU9) is 434 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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