Olfactory receptor 2Y1 (OR2Y1)
Homo sapiens — UniProt Q8NGV0
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 2Y1 (OR2Y1) is a protein from Homo sapiens identified by UniProt accession Q8NGV0, 311 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q8NGV0; gene symbol OR2Y1.
- Organism: Homo sapiens.
- Length: 311 amino acids.
- Top disease associations (Open Targets): medulloblastoma, breast adenocarcinoma and acute myeloid leukemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 2Y1 |
|---|---|
| UniProt accession | Q8NGV0 |
| Gene | OR2Y1 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- medulloblastoma · score 0.21
- breast adenocarcinoma · score 0.18
- acute myeloid leukemia · score 0.14
- MODY · score 0.10
- type 2 diabetes mellitus · score 0.08
- type 1 diabetes mellitus · score 0.06
- diabetes mellitus, transient neonatal, 2 · score 0.06
- uridine-cytidineuria · score 0.05
- hyperinsulinism due to glucokinase deficiency · score 0.05
- juvenile cataract-microcornea-renal glucosuria syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGV0-F1 | alphafold | PREDICTED | 89.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGV0.
Amino-acid sequence (311 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR2Y1?
The strongest Open Targets associations for OR2Y1 are medulloblastoma, breast adenocarcinoma, acute myeloid leukemia, MODY and type 2 diabetes mellitus.
How long is the OR2Y1 protein?
The Homo sapiens OR2Y1 protein (UniProt Q8NGV0) is 311 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGV0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGV0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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