Olfactory receptor 5H6 (OR5H6)
Homo sapiens — UniProt Q8NGV6
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 5H6 (OR5H6) is a protein from Homo sapiens identified by UniProt accession Q8NGV6, 325 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q8NGV6; gene symbol OR5H6.
- Organism: Homo sapiens.
- Length: 325 amino acids.
- Top disease associations (Open Targets): neuroblastoma, prostate adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 5H6 |
|---|---|
| UniProt accession | Q8NGV6 |
| Gene | OR5H6 |
| Organism | Homo sapiens |
| Length | 325 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- checkup · score 0.14
- mean platelet volume · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGV6-F1 | alphafold | PREDICTED | 85.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGV6.
Amino-acid sequence (325 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR5H6?
The strongest Open Targets associations for OR5H6 are neuroblastoma, prostate adenocarcinoma, ovarian cancer, breast adenocarcinoma and checkup.
How long is the OR5H6 protein?
The Homo sapiens OR5H6 protein (UniProt Q8NGV6) is 325 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGV6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGV6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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