Olfactory receptor 5H2 (OR5H2)
Homo sapiens — UniProt Q8NGV7
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 5H2 (OR5H2) is a protein from Homo sapiens identified by UniProt accession Q8NGV7, 309 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q8NGV7; gene symbol OR5H2.
- Organism: Homo sapiens.
- Length: 309 amino acids.
- Top disease associations (Open Targets): ovarian cancer, low grade glioma and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 5H2 |
|---|---|
| UniProt accession | Q8NGV7 |
| Gene | OR5H2 |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- checkup · score 0.05
- central corneal thickness · score 0.02
- hyperinsulinemic hypoglycemia, familial, 4 · score 0.01
- gastric carcinoma · score 0.01
- Leigh syndrome · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGV7-F1 | alphafold | PREDICTED | 88.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGV7.
Amino-acid sequence (309 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR5H2?
The strongest Open Targets associations for OR5H2 are ovarian cancer, low grade glioma, breast adenocarcinoma, multiple myeloma and checkup.
How long is the OR5H2 protein?
The Homo sapiens OR5H2 protein (UniProt Q8NGV7) is 309 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGV7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGV7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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