Olfactory receptor 6B3 (OR6B3)
Homo sapiens — UniProt Q8NGW1
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 6B3 (OR6B3) is a protein from Homo sapiens identified by UniProt accession Q8NGW1, 331 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8NGW1; gene symbol OR6B3.
- Organism: Homo sapiens.
- Length: 331 amino acids.
- Top disease associations (Open Targets): neuroblastoma, ovarian cancer and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 6B3 |
|---|---|
| UniProt accession | Q8NGW1 |
| Gene | OR6B3 |
| Organism | Homo sapiens |
| Length | 331 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- central nervous system cancer · score 0.03
- sensory perception of smell · score 0.02
- myopia · score 0.00
- Myopia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGW1-F1 | alphafold | PREDICTED | 82.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGW1.
Amino-acid sequence (331 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR6B3?
The strongest Open Targets associations for OR6B3 are neuroblastoma, ovarian cancer, breast adenocarcinoma, central nervous system cancer and sensory perception of smell.
How long is the OR6B3 protein?
The Homo sapiens OR6B3 protein (UniProt Q8NGW1) is 331 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGW1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGW1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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