Olfactory receptor 10K1 (OR10K1)
Homo sapiens — UniProt Q8NGX5
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 10K1 (OR10K1) is a protein from Homo sapiens identified by UniProt accession Q8NGX5, 313 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q8NGX5; gene symbol OR10K1.
- Organism: Homo sapiens.
- Length: 313 amino acids.
- Top disease associations (Open Targets): thyroid gland adenocarcinoma, prostate adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 10K1 |
|---|---|
| UniProt accession | Q8NGX5 |
| Gene | OR10K1 |
| Organism | Homo sapiens |
| Length | 313 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- pancreatic adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- reticulocyte count · score 0.10
- mean reticulocyte volume · score 0.08
- reticulocyte measurement · score 0.05
- mean corpuscular volume · score 0.03
- Red cell distribution width · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGX5-F1 | alphafold | PREDICTED | 88.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGX5.
Amino-acid sequence (313 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR10K1?
The strongest Open Targets associations for OR10K1 are thyroid gland adenocarcinoma, prostate adenocarcinoma, ovarian cancer, pancreatic adenocarcinoma and breast adenocarcinoma.
How long is the OR10K1 protein?
The Homo sapiens OR10K1 protein (UniProt Q8NGX5) is 313 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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