Olfactory receptor 10K1 (OR10K1)

About Olfactory receptor 10K1

Olfactory receptor 10K1 (OR10K1) is a protein from Homo sapiens identified by UniProt accession Q8NGX5, 313 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Olfactory receptor 10K1
UniProt accession	Q8NGX5
Gene	OR10K1
Organism	Homo sapiens
Length	313 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

thyroid gland adenocarcinoma · score 0.22
prostate adenocarcinoma · score 0.18
ovarian cancer · score 0.18
pancreatic adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
reticulocyte count · score 0.10
mean reticulocyte volume · score 0.08
reticulocyte measurement · score 0.05
mean corpuscular volume · score 0.03
Red cell distribution width · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGX5-F1	alphafold	PREDICTED	88.23	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGX5.

Amino-acid sequence (313 residues)

MEQVNKTVVR EFVVLGFSSL ARLQQLLFVI FLLLYLFTLG TNAIIISTIV LDRALHTPMY FFLAILSCSE ICYTFVIVPK MLVDLLSQKK TISFLGCAIQ MFSFLFFGSS HSFLLAAMGY DRYMAICNPL RYSVLMGHGV CMGLMAAACA CGFTVSLVTT SLVFHLPFHS SNQLHHFFCD ISPVLKLASQ HSGFSQLVIF MLGVFALVIP LLLILVSYIR IISAILKIPS SVGRYKTFST CASHLIVVTV HYSCASFIYL RPKTNYTSSQ DTLISVSYTI LTPLFNPMIY SLRNKEFKSA LRRTIGQTFY PLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards