Olfactory receptor 2L8 (OR2L8)
Homo sapiens — UniProt Q8NGY9
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 2L8 (OR2L8) is a protein from Homo sapiens identified by UniProt accession Q8NGY9, 312 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8NGY9; gene symbol OR2L8.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): ovarian cancer, low grade glioma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 2L8 |
|---|---|
| UniProt accession | Q8NGY9 |
| Gene | OR2L8 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- AIDS dementia · score 0.01
- chronic myelogenous leukemia · score 0.01
- diabetes mellitus · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGY9-F1 | alphafold | PREDICTED | 91.00 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGY9.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR2L8?
The strongest Open Targets associations for OR2L8 are ovarian cancer, low grade glioma, clear cell renal carcinoma, breast adenocarcinoma and multiple myeloma.
How long is the OR2L8 protein?
The Homo sapiens OR2L8 protein (UniProt Q8NGY9) is 312 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGY9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGY9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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