Olfactory receptor 2G2 (OR2G2)

About Olfactory receptor 2G2

Olfactory receptor 2G2 (OR2G2) is a protein from Homo sapiens identified by UniProt accession Q8NGZ5, 317 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Olfactory receptor 2G2
UniProt accession	Q8NGZ5
Gene	OR2G2
Organism	Homo sapiens
Length	317 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

neuroblastoma · score 0.21
clear cell renal carcinoma · score 0.18
breast adenocarcinoma · score 0.18
mean platelet volume · score 0.06
platelet count · score 0.06
reticulocyte count · score 0.05
urticaria · score 0.05
mean corpuscular volume · score 0.05
liver fibrosis measurement · score 0.05
platelet component distribution width · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGZ5-F1	alphafold	PREDICTED	82.35	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGZ5.

Amino-acid sequence (317 residues)

MGMVRHTNES NLAGFILLGF SDYPQLQKVL FVLILILYLL TILGNTTIIL VSRLEPKLHM PMYFFLSHLS FLYRCFTSSV IPQLLVNLWE PMKTIAYGGC LVHLYNSHAL GSTECVLPAV MSCDRYVAVC RPLHYTVLMH IHLCMALASM AWLSGIATTL VQSTLTLQLP FCGHRQVDHF ICEVPVLIKL ACVGTTFNEA ELFVASILFL IVPVSFILVS SGYIAHAVLR IKSATRRQKA FGTCFSHLTV VTIFYGTIIF MYLQPAKSRS RDQGKFVSLF YTVVTRMLNP LIYTLRIKEV KGALKKVLAK ALGVNIL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards