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Olfactory receptor 2G2 (OR2G2)

Homo sapiens — UniProt Q8NGZ5

Gene: OR2G2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Olfactory receptor 2G2 (OR2G2) is a protein from Homo sapiens identified by UniProt accession Q8NGZ5, 317 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

  • UniProt accession: Q8NGZ5; gene symbol OR2G2.
  • Organism: Homo sapiens.
  • Length: 317 amino acids.
  • Top disease associations (Open Targets): neuroblastoma, clear cell renal carcinoma and breast adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOlfactory receptor 2G2
UniProt accessionQ8NGZ5
GeneOR2G2
OrganismHomo sapiens
Length317 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (22)

Diseases linked to this target (Open Targets).

  • neuroblastoma · score 0.21
  • clear cell renal carcinoma · score 0.18
  • breast adenocarcinoma · score 0.18
  • mean platelet volume · score 0.06
  • platelet count · score 0.06
  • reticulocyte count · score 0.05
  • urticaria · score 0.05
  • mean corpuscular volume · score 0.05
  • liver fibrosis measurement · score 0.05
  • platelet component distribution width · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NGZ5-F1alphafoldPREDICTED82.35—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGZ5.

Amino-acid sequence (317 residues)

MGMVRHTNES NLAGFILLGF SDYPQLQKVL FVLILILYLL TILGNTTIIL VSRLEPKLHM PMYFFLSHLS FLYRCFTSSV IPQLLVNLWE PMKTIAYGGC LVHLYNSHAL GSTECVLPAV MSCDRYVAVC RPLHYTVLMH IHLCMALASM AWLSGIATTL VQSTLTLQLP FCGHRQVDHF ICEVPVLIKL ACVGTTFNEA ELFVASILFL IVPVSFILVS SGYIAHAVLR IKSATRRQKA FGTCFSHLTV VTIFYGTIIF MYLQPAKSRS RDQGKFVSLF YTVVTRMLNP LIYTLRIKEV KGALKKVLAK ALGVNIL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OR2G2?

The strongest Open Targets associations for OR2G2 are neuroblastoma, clear cell renal carcinoma, breast adenocarcinoma, mean platelet volume and platelet count.

How long is the OR2G2 protein?

The Homo sapiens OR2G2 protein (UniProt Q8NGZ5) is 317 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NGZ5
GeneOR2G2
OrganismHomo sapiens
Length317
Binders0
Diseases22
View on UniProt