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Olfactory receptor 6F1 (OR6F1)

Homo sapiens — UniProt Q8NGZ6

Gene: OR6F1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Olfactory receptor 6F1 (OR6F1) is a protein from Homo sapiens identified by UniProt accession Q8NGZ6, 308 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

  • UniProt accession: Q8NGZ6; gene symbol OR6F1.
  • Organism: Homo sapiens.
  • Length: 308 amino acids.
  • Top disease associations (Open Targets): mean platelet volume, clear cell renal carcinoma and low grade glioma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOlfactory receptor 6F1
UniProt accessionQ8NGZ6
GeneOR6F1
OrganismHomo sapiens
Length308 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (10)

Diseases linked to this target (Open Targets).

  • mean platelet volume · score 0.41
  • clear cell renal carcinoma · score 0.18
  • low grade glioma · score 0.18
  • breast adenocarcinoma · score 0.18
  • multiple myeloma · score 0.16
  • reticulocyte count · score 0.07
  • pain · score 0.06
  • reticulocyte measurement · score 0.03
  • gastric carcinoma · score 0.02
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NGZ6-F1alphafoldPREDICTED88.09—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGZ6.

Amino-acid sequence (308 residues)

MDTGNKTLPQ DFLLLGFPGS QTLQLSLFML FLVMYILTVS GNVAILMLVS TSHQLHTPMY FFLSNLSFLE IWYTTAAVPK ALAILLGRSQ TISFTSCLLQ MYFVFSLGCT EYFLLAAMAY DRCLAICYPL HYGAIMSSLL SAQLALGSWV CGFVAIAVPT ALISGLSFCG PRAINHFFCD IAPWIALACT NTQAVELVAF VIAVVVILSS CLITFVSYVY IISTILRIPS ASGRSKAFST CSSHLTVVLI WYGSTVFLHV RTSIKDALDL IKAVHVLNTV VTPVLNPFIY TLRNKEVRET LLKKWKGK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OR6F1?

The strongest Open Targets associations for OR6F1 are mean platelet volume, clear cell renal carcinoma, low grade glioma, breast adenocarcinoma and multiple myeloma.

How long is the OR6F1 protein?

The Homo sapiens OR6F1 protein (UniProt Q8NGZ6) is 308 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NGZ6
GeneOR6F1
OrganismHomo sapiens
Length308
Binders0
Diseases10
View on UniProt