Tubulin polyglutamylase TTLL11 (TTLL11)
Homo sapiens — UniProt Q8NHH1
Data last refreshed: (UniProt release unknown)
Key facts
Tubulin polyglutamylase TTLL11 (TTLL11) is a protein from Homo sapiens identified by UniProt accession Q8NHH1, 710 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q8NHH1; gene symbol TTLL11.
- Organism: Homo sapiens.
- Length: 710 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, body mass index and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tubulin polyglutamylase TTLL11 |
|---|---|
| UniProt accession | Q8NHH1 |
| Gene | TTLL11 |
| Organism | Homo sapiens |
| Length | 710 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.43
- body mass index · score 0.42
- body fat percentage · score 0.41
- lean body mass · score 0.35
- platelet count · score 0.35
- mathematical ability · score 0.34
- heel bone mineral density · score 0.33
- fat body mass · score 0.33
- protein measurement · score 0.33
- intelligence · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NHH1-F1 | alphafold | PREDICTED | 76.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NHH1.
Amino-acid sequence (710 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TTLL11?
The strongest Open Targets associations for TTLL11 are self reported educational attainment, body mass index, body fat percentage, lean body mass and platelet count.
How long is the TTLL11 protein?
The Homo sapiens TTLL11 protein (UniProt Q8NHH1) is 710 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NHH1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NHH1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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