Putative aminopeptidase PLBD2 (PLBD2)
Homo sapiens — UniProt Q8NHP8
Data last refreshed: (UniProt release unknown)
Key facts
Putative aminopeptidase PLBD2 (PLBD2) is a protein from Homo sapiens identified by UniProt accession Q8NHP8, 589 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q8NHP8; gene symbol PLBD2.
- Organism: Homo sapiens.
- Length: 589 amino acids.
- Top disease associations (Open Targets): blood protein measurement, body mass index and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative aminopeptidase PLBD2 |
|---|---|
| UniProt accession | Q8NHP8 |
| Gene | PLBD2 |
| Organism | Homo sapiens |
| Length | 589 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.14
- body mass index · score 0.09
- attention deficit hyperactivity disorder · score 0.06
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.05
- hemoglobin D disease · score 0.05
- Tourette syndrome · score 0.05
- attention deficit-hyperactivity disorder 8 · score 0.05
- schizophrenia 15 · score 0.05
- delta-beta-thalassemia · score 0.05
- dominant beta-thalassemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NHP8-F1 | alphafold | PREDICTED | 91.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NHP8.
Amino-acid sequence (589 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLBD2?
The strongest Open Targets associations for PLBD2 are blood protein measurement, body mass index, attention deficit hyperactivity disorder, hereditary persistence of fetal hemoglobin-sickle cell disease syndrome and hemoglobin D disease.
How long is the PLBD2 protein?
The Homo sapiens PLBD2 protein (UniProt Q8NHP8) is 589 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NHP8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NHP8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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