Beta-1,4 N-acetylgalactosaminyltransferase 2 (B4GALNT2)
Homo sapiens — UniProt Q8NHY0
Data last refreshed: (UniProt release unknown)
Key facts
Beta-1,4 N-acetylgalactosaminyltransferase 2 (B4GALNT2) is a protein from Homo sapiens identified by UniProt accession Q8NHY0, 566 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q8NHY0; gene symbol B4GALNT2.
- Organism: Homo sapiens.
- Length: 566 amino acids.
- Top disease associations (Open Targets): neutrophil count, HMG CoA reductase inhibitor use measurement and Calcium channel blocker use measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-1,4 N-acetylgalactosaminyltransferase 2 |
|---|---|
| UniProt accession | Q8NHY0 |
| Gene | B4GALNT2 |
| Organism | Homo sapiens |
| Length | 566 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.24
- HMG CoA reductase inhibitor use measurement · score 0.22
- Calcium channel blocker use measurement · score 0.22
- leukocyte count · score 0.22
- Agents acting on the renin-angiotensin system use measurement · score 0.21
- monocyte percentage of leukocytes · score 0.17
- age at onset · score 0.16
- Myopia · score 0.16
- refractive error · score 0.16
- sex hormone-binding globulin measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NHY0-F1 | alphafold | PREDICTED | 83.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NHY0.
Amino-acid sequence (566 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with B4GALNT2?
The strongest Open Targets associations for B4GALNT2 are neutrophil count, HMG CoA reductase inhibitor use measurement, Calcium channel blocker use measurement, leukocyte count and Agents acting on the renin-angiotensin system use measurement.
How long is the B4GALNT2 protein?
The Homo sapiens B4GALNT2 protein (UniProt Q8NHY0) is 566 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NHY0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NHY0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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