Nuclear receptor coactivator 7 (NCOA7)
Homo sapiens — UniProt Q8NI08
Data last refreshed: (UniProt release unknown)
Key facts
Nuclear receptor coactivator 7 (NCOA7) is a protein from Homo sapiens identified by UniProt accession Q8NI08, 942 residues long. MolForge cross-references it against 0 known binders and 112 disease associations.
- UniProt accession: Q8NI08; gene symbol NCOA7.
- Organism: Homo sapiens.
- Length: 942 amino acids.
- Target class: Nuclear receptor.
- Top disease associations (Open Targets): reticulocyte count, reticulocyte measurement and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nuclear receptor coactivator 7 |
|---|---|
| UniProt accession | Q8NI08 |
| Gene | NCOA7 |
| Organism | Homo sapiens |
| Length | 942 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Nuclear receptor (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (112)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.48
- reticulocyte measurement · score 0.45
- urate measurement · score 0.43
- electrocardiography · score 0.43
- hemoglobin measurement · score 0.42
- erythrocyte count · score 0.42
- Brugada syndrome · score 0.40
- systolic blood pressure · score 0.38
- body mass index · score 0.38
- Immature Reticulocyte Fraction Measurement · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NI08-F1 | alphafold | PREDICTED | 55.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NI08.
Amino-acid sequence (942 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NCOA7?
The strongest Open Targets associations for NCOA7 are reticulocyte count, reticulocyte measurement, urate measurement, electrocardiography and hemoglobin measurement.
How long is the NCOA7 protein?
The Homo sapiens NCOA7 protein (UniProt Q8NI08) is 942 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NI08 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NI08 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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