Ras and Rab interactor 3 (RIN3)
Homo sapiens — UniProt Q8TB24
Data last refreshed: (UniProt release unknown)
Key facts
Ras and Rab interactor 3 (RIN3) is a protein from Homo sapiens identified by UniProt accession Q8TB24, 985 residues long. MolForge cross-references it against 0 known binders and 151 disease associations.
- UniProt accession: Q8TB24; gene symbol RIN3.
- Organism: Homo sapiens.
- Length: 985 amino acids.
- Top disease associations (Open Targets): neutrophil count, eosinophil count and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras and Rab interactor 3 |
|---|---|
| UniProt accession | Q8TB24 |
| Gene | RIN3 |
| Organism | Homo sapiens |
| Length | 985 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (151)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.53
- eosinophil count · score 0.53
- monocyte count · score 0.52
- leukocyte count · score 0.51
- lean body mass · score 0.51
- body fat percentage · score 0.50
- bone density · score 0.50
- lymphocyte percentage of leukocytes · score 0.50
- mean platelet volume · score 0.49
- vital capacity · score 0.49
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TB24-F1 | alphafold | PREDICTED | 61.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TB24.
Amino-acid sequence (985 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RIN3?
The strongest Open Targets associations for RIN3 are neutrophil count, eosinophil count, monocyte count, leukocyte count and lean body mass.
How long is the RIN3 protein?
The Homo sapiens RIN3 protein (UniProt Q8TB24) is 985 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TB24 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TB24 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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