Proline-rich protein 7 (PRR7)
Homo sapiens — UniProt Q8TB68
Data last refreshed: (UniProt release unknown)
Key facts
Proline-rich protein 7 (PRR7) is a protein from Homo sapiens identified by UniProt accession Q8TB68, 274 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q8TB68; gene symbol PRR7.
- Organism: Homo sapiens.
- Length: 274 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, mathematical ability and intelligence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proline-rich protein 7 |
|---|---|
| UniProt accession | Q8TB68 |
| Gene | PRR7 |
| Organism | Homo sapiens |
| Length | 274 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.20
- mathematical ability · score 0.17
- intelligence · score 0.17
- chronotype measurement · score 0.15
- brain measurement · score 0.13
- verbal-numerical reasoning measurement · score 0.11
- cognitive function measurement · score 0.10
- neoplasm · score 0.08
- cancer · score 0.08
- hepatocellular carcinoma · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TB68-F1 | alphafold | PREDICTED | 56.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TB68.
Amino-acid sequence (274 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRR7?
The strongest Open Targets associations for PRR7 are self reported educational attainment, mathematical ability, intelligence, chronotype measurement and brain measurement.
How long is the PRR7 protein?
The Homo sapiens PRR7 protein (UniProt Q8TB68) is 274 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TB68 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TB68 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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