Protein cornichon homolog 3 (CNIH3)
Homo sapiens — UniProt Q8TBE1
Data last refreshed: (UniProt release unknown)
Key facts
Protein cornichon homolog 3 (CNIH3) is a protein from Homo sapiens identified by UniProt accession Q8TBE1, 160 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q8TBE1; gene symbol CNIH3.
- Organism: Homo sapiens.
- Length: 160 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, neutrophil count and opioid dependence.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein cornichon homolog 3 |
|---|---|
| UniProt accession | Q8TBE1 |
| Gene | CNIH3 |
| Organism | Homo sapiens |
| Length | 160 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.43
- neutrophil count · score 0.37
- opioid dependence · score 0.27
- leukocyte count · score 0.24
- myeloid white cell count · score 0.24
- sitting height measurement · score 0.23
- forced expiratory volume · score 0.22
- body height · score 0.21
- protein measurement · score 0.21
- low density lipoprotein cholesterol measurement · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBE1-F1 | alphafold | PREDICTED | 84.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBE1.
Amino-acid sequence (160 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNIH3?
The strongest Open Targets associations for CNIH3 are Red cell distribution width, neutrophil count, opioid dependence, leukocyte count and myeloid white cell count.
How long is the CNIH3 protein?
The Homo sapiens CNIH3 protein (UniProt Q8TBE1) is 160 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBE1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBE1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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