Protein FAM81A (FAM81A)
Homo sapiens — UniProt Q8TBF8
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM81A (FAM81A) is a protein from Homo sapiens identified by UniProt accession Q8TBF8, 368 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q8TBF8; gene symbol FAM81A.
- Organism: Homo sapiens.
- Length: 368 amino acids.
- Top disease associations (Open Targets): drug use measurement, hemoglobin H disease and dominant beta-thalassemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM81A |
|---|---|
| UniProt accession | Q8TBF8 |
| Gene | FAM81A |
| Organism | Homo sapiens |
| Length | 368 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- drug use measurement · score 0.06
- hemoglobin H disease · score 0.03
- dominant beta-thalassemia · score 0.03
- glycoprotein storage disease · score 0.03
- hemoglobin C-beta-thalassemia syndrome · score 0.03
- combined immunodeficiency due to OX40 deficiency · score 0.03
- neuronal ceroid lipofuscinosis 1 · score 0.03
- Hyperlipoproteinemia type 1 · score 0.03
- erythroleukemia, familial, susceptibility to · score 0.03
- hereditary neutrophilia · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBF8-F1 | alphafold | PREDICTED | 82.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBF8.
Amino-acid sequence (368 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM81A?
The strongest Open Targets associations for FAM81A are drug use measurement, hemoglobin H disease, dominant beta-thalassemia, glycoprotein storage disease and hemoglobin C-beta-thalassemia syndrome.
How long is the FAM81A protein?
The Homo sapiens FAM81A protein (UniProt Q8TBF8) is 368 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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