Synaptoporin (SYNPR)
Homo sapiens — UniProt Q8TBG9
Data last refreshed: (UniProt release unknown)
Key facts
Synaptoporin (SYNPR) is a protein from Homo sapiens identified by UniProt accession Q8TBG9, 265 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q8TBG9; gene symbol SYNPR.
- Organism: Homo sapiens.
- Length: 265 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, diffuse plaque measurement and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptoporin |
|---|---|
| UniProt accession | Q8TBG9 |
| Gene | SYNPR |
| Organism | Homo sapiens |
| Length | 265 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.40
- diffuse plaque measurement · score 0.31
- neurofibrillary tangles measurement · score 0.30
- chronotype measurement · score 0.13
- mathematical ability · score 0.12
- body mass index · score 0.11
- drug use measurement · score 0.08
- astrocytoma · score 0.06
- glioblastoma multiforme · score 0.05
- ependymoma · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBG9-F1 | alphafold | PREDICTED | 76.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBG9.
Amino-acid sequence (265 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYNPR?
The strongest Open Targets associations for SYNPR are gut microbiome measurement, diffuse plaque measurement, neurofibrillary tangles measurement, chronotype measurement and mathematical ability.
How long is the SYNPR protein?
The Homo sapiens SYNPR protein (UniProt Q8TBG9) is 265 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBG9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBG9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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