DnaJ homolog subfamily B member 14 (DNAJB14)
Homo sapiens — UniProt Q8TBM8
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily B member 14 (DNAJB14) is a protein from Homo sapiens identified by UniProt accession Q8TBM8, 379 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q8TBM8; gene symbol DNAJB14.
- Organism: Homo sapiens.
- Length: 379 amino acids.
- Top disease associations (Open Targets): lean body mass, mean corpuscular volume and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily B member 14 |
|---|---|
| UniProt accession | Q8TBM8 |
| Gene | DNAJB14 |
| Organism | Homo sapiens |
| Length | 379 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.27
- mean corpuscular volume · score 0.21
- mean corpuscular hemoglobin concentration · score 0.17
- platelet count · score 0.16
- fat body mass · score 0.14
- appendicular lean mass · score 0.13
- reticulocyte measurement · score 0.13
- reticulocyte count · score 0.12
- mean corpuscular hemoglobin · score 0.11
- mean platelet volume · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBM8-F1 | alphafold | PREDICTED | 75.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBM8.
Amino-acid sequence (379 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJB14?
The strongest Open Targets associations for DNAJB14 are lean body mass, mean corpuscular volume, mean corpuscular hemoglobin concentration, platelet count and fat body mass.
How long is the DNAJB14 protein?
The Homo sapiens DNAJB14 protein (UniProt Q8TBM8) is 379 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBM8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBM8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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