Protein kish-A (TMEM167A)
Homo sapiens — UniProt Q8TBQ9
Data last refreshed: (UniProt release unknown)
Key facts
Protein kish-A (TMEM167A) is a protein from Homo sapiens identified by UniProt accession Q8TBQ9, 72 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q8TBQ9; gene symbol TMEM167A.
- Organism: Homo sapiens.
- Length: 72 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cortical surface area measurement and balding measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein kish-A |
|---|---|
| UniProt accession | Q8TBQ9 |
| Gene | TMEM167A |
| Organism | Homo sapiens |
| Length | 72 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- cortical surface area measurement · score 0.24
- balding measurement · score 0.24
- electrocardiography · score 0.22
- white matter microstructure measurement · score 0.21
- brain volume measurement · score 0.15
- heel bone mineral density · score 0.14
- chin morphology measurement · score 0.12
- facial morphology measurement · score 0.12
- hair shape measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBQ9-F1 | alphafold | PREDICTED | 66.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBQ9.
Amino-acid sequence (72 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM167A?
The strongest Open Targets associations for TMEM167A are neurodegenerative disease, cortical surface area measurement, balding measurement, electrocardiography and white matter microstructure measurement.
How long is the TMEM167A protein?
The Homo sapiens TMEM167A protein (UniProt Q8TBQ9) is 72 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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