Coiled-coil domain-containing protein 110 (CCDC110)
Homo sapiens — UniProt Q8TBZ0
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 110 (CCDC110) is a protein from Homo sapiens identified by UniProt accession Q8TBZ0, 833 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8TBZ0; gene symbol CCDC110.
- Organism: Homo sapiens.
- Length: 833 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, breast carcinoma and idiopathic hypereosinophilic syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 110 |
|---|---|
| UniProt accession | Q8TBZ0 |
| Gene | CCDC110 |
| Organism | Homo sapiens |
| Length | 833 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- breast carcinoma · score 0.04
- idiopathic hypereosinophilic syndrome · score 0.04
- type 2 diabetes mellitus · score 0.03
- hemoglobin H disease · score 0.03
- glycoprotein storage disease · score 0.03
- dominant beta-thalassemia · score 0.03
- hemoglobin C-beta-thalassemia syndrome · score 0.03
- combined immunodeficiency due to OX40 deficiency · score 0.03
- Hyperlipoproteinemia type 1 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBZ0-F1 | alphafold | PREDICTED | 66.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBZ0.
Amino-acid sequence (833 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC110?
The strongest Open Targets associations for CCDC110 are neurodegenerative disease, breast carcinoma, idiopathic hypereosinophilic syndrome, type 2 diabetes mellitus and hemoglobin H disease.
How long is the CCDC110 protein?
The Homo sapiens CCDC110 protein (UniProt Q8TBZ0) is 833 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBZ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBZ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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