WD repeat-containing protein 20 (WDR20)
Homo sapiens — UniProt Q8TBZ3
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 20 (WDR20) is a protein from Homo sapiens identified by UniProt accession Q8TBZ3, 569 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q8TBZ3; gene symbol WDR20.
- Organism: Homo sapiens.
- Length: 569 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte count and Red cell distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 20 |
|---|---|
| UniProt accession | Q8TBZ3 |
| Gene | WDR20 |
| Organism | Homo sapiens |
| Length | 569 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- reticulocyte count · score 0.33
- Red cell distribution width · score 0.32
- Parkinson disease · score 0.24
- Alzheimer disease · score 0.24
- lysosomal storage disease · score 0.24
- multiple sclerosis · score 0.24
- total blood protein measurement · score 0.24
- breast adenocarcinoma · score 0.23
- mean corpuscular volume · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TBZ3-F1 | alphafold | PREDICTED | 77.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBZ3.
Amino-acid sequence (569 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR20?
The strongest Open Targets associations for WDR20 are neurodegenerative disease, reticulocyte count, Red cell distribution width, Parkinson disease and Alzheimer disease.
How long is the WDR20 protein?
The Homo sapiens WDR20 protein (UniProt Q8TBZ3) is 569 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TBZ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TBZ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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