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Zinc finger protein 564 (ZNF564)

Homo sapiens — UniProt Q8TBZ8

Gene: ZNF564Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 564 (ZNF564) is a protein from Homo sapiens identified by UniProt accession Q8TBZ8, 553 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

  • UniProt accession: Q8TBZ8; gene symbol ZNF564.
  • Organism: Homo sapiens.
  • Length: 553 amino acids.
  • Top disease associations (Open Targets): alpha-mannosidosis, mean corpuscular volume and erythrocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 564
UniProt accessionQ8TBZ8
GeneZNF564
OrganismHomo sapiens
Length553 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (5)

Diseases linked to this target (Open Targets).

  • alpha-mannosidosis · score 0.34
  • mean corpuscular volume · score 0.02
  • erythrocyte count · score 0.02
  • hemoglobin measurement · score 0.02
  • type 2 diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8TBZ8-F1alphafoldPREDICTED77.93—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TBZ8.

Amino-acid sequence (553 residues)

MDSVASEDVA VNFTLEEWAL LDPSQKKLYR DVMRETFRNL ACVGKKWEDQ SIEDWYKNQG RILRNHMEEG LSESKEYDQC GEAFSQILNL NLNKKIPTIV RPCECSLCGK VFMHHSSLSR HIRSHLGHKP YDYQEYGEKP YKCKQCGKAF SSCQSFRRHE RTHTGEKPYA CPECGKAFIS LPSVRRHMIK HTGDGPYKCQ ECGKAFDRPS LFQIHERTHT GEKPYECQEC AKAFISLPSF QRHMIRHTGD GPYKCQECGK AFDRPSLFRI HERTHTGEKP HECKQCGKAF ISFTNFQSHM IRHTGDGPYK CKVCGRAFIF PSYVRKHERT HTGEKPYECN KCGKTFSSSS NVRTHERTHT GEKPYECKEC GKAFISLPSV RRHMIKHTGD GPYKCQVCGR AFDCPSSFQI HERTHTGEKP YECQVCGKAF ISLKRIRKHM ILHTGDGPYK CQVCGKAFDC PSSVRTHERT HTGEKPYECK ECGKAFNYAS SIRIHERTHT GEKPYECKQC GKTFSYSSSF QRHERAHNGD KPYVKNVGKL SFITQPSNTC ENE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF564?

The strongest Open Targets associations for ZNF564 are alpha-mannosidosis, mean corpuscular volume, erythrocyte count, hemoglobin measurement and type 2 diabetes mellitus.

How long is the ZNF564 protein?

The Homo sapiens ZNF564 protein (UniProt Q8TBZ8) is 553 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8TBZ8
GeneZNF564
OrganismHomo sapiens
Length553
Binders0
Diseases5
View on UniProt