Mirror-image polydactyly gene 1 protein (MIPOL1)
Homo sapiens — UniProt Q8TD10
Data last refreshed: (UniProt release unknown)
Key facts
Mirror-image polydactyly gene 1 protein (MIPOL1) is a protein from Homo sapiens identified by UniProt accession Q8TD10, 442 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q8TD10; gene symbol MIPOL1.
- Organism: Homo sapiens.
- Length: 442 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mirror-image polydactyly gene 1 protein |
|---|---|
| UniProt accession | Q8TD10 |
| Gene | MIPOL1 |
| Organism | Homo sapiens |
| Length | 442 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.49
- mean corpuscular hemoglobin · score 0.48
- mean corpuscular hemoglobin concentration · score 0.44
- reticulocyte count · score 0.43
- erythrocyte count · score 0.43
- eosinophil count · score 0.40
- red blood cell density measurement · score 0.40
- mean reticulocyte volume · score 0.40
- neurodegenerative disease · score 0.35
- creatinine measurement · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TD10-F1 | alphafold | PREDICTED | 77.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TD10.
Amino-acid sequence (442 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIPOL1?
The strongest Open Targets associations for MIPOL1 are mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, reticulocyte count and erythrocyte count.
How long is the MIPOL1 protein?
The Homo sapiens MIPOL1 protein (UniProt Q8TD10) is 442 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TD10 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TD10 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.