Hepatitis A virus cellular receptor 2 (HAVCR2)
Homo sapiens — UniProt Q8TDQ0
Data last refreshed: (UniProt release unknown)
Key facts
Hepatitis A virus cellular receptor 2 (HAVCR2) is a protein from Homo sapiens identified by UniProt accession Q8TDQ0, 301 residues long. MolForge cross-references it against 0 known binders and 597 disease associations.
- UniProt accession: Q8TDQ0; gene symbol HAVCR2.
- Organism: Homo sapiens.
- Length: 301 amino acids.
- Top disease associations (Open Targets): Subcutaneous Panniculitis-Like T-Cell Lymphoma, blood protein measurement and myelodysplastic syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Hepatitis A virus cellular receptor 2 |
|---|---|
| UniProt accession | Q8TDQ0 |
| Gene | HAVCR2 |
| Organism | Homo sapiens |
| Length | 301 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (597)
Diseases linked to this target (Open Targets).
- Subcutaneous Panniculitis-Like T-Cell Lymphoma · score 0.69
- blood protein measurement · score 0.38
- myelodysplastic syndrome · score 0.32
- neoplasm · score 0.31
- hepatitis A virus cellular receptor 2 measurement · score 0.30
- low density lipoprotein cholesterol measurement · score 0.28
- late-onset Alzheimers disease · score 0.27
- acute myeloid leukemia · score 0.14
- inflammatory bowel disease · score 0.14
- melanoma · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDQ0-F1 | alphafold | PREDICTED | 71.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDQ0.
Amino-acid sequence (301 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HAVCR2?
The strongest Open Targets associations for HAVCR2 are Subcutaneous Panniculitis-Like T-Cell Lymphoma, blood protein measurement, myelodysplastic syndrome, neoplasm and hepatitis A virus cellular receptor 2 measurement.
How long is the HAVCR2 protein?
The Homo sapiens HAVCR2 protein (UniProt Q8TDQ0) is 301 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDQ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDQ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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