CMRF35-like molecule 1 (CD300LF)
Homo sapiens — UniProt Q8TDQ1
Data last refreshed: (UniProt release unknown)
Key facts
CMRF35-like molecule 1 (CD300LF) is a protein from Homo sapiens identified by UniProt accession Q8TDQ1, 290 residues long. MolForge cross-references it against 0 known binders and 120 disease associations.
- UniProt accession: Q8TDQ1; gene symbol CD300LF.
- Organism: Homo sapiens.
- Length: 290 amino acids.
- Top disease associations (Open Targets): monocyte count, C-reactive protein measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CMRF35-like molecule 1 |
|---|---|
| UniProt accession | Q8TDQ1 |
| Gene | CD300LF |
| Organism | Homo sapiens |
| Length | 290 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (120)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.36
- C-reactive protein measurement · score 0.35
- blood protein measurement · score 0.31
- myeloid white cell count · score 0.31
- Red cell distribution width · score 0.31
- leukocyte count · score 0.27
- fibrinogen measurement · score 0.27
- neutrophil count · score 0.26
- lymphocyte count · score 0.26
- protein measurement · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDQ1-F1 | alphafold | PREDICTED | 72.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDQ1.
Amino-acid sequence (290 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CD300LF?
The strongest Open Targets associations for CD300LF are monocyte count, C-reactive protein measurement, blood protein measurement, myeloid white cell count and Red cell distribution width.
How long is the CD300LF protein?
The Homo sapiens CD300LF protein (UniProt Q8TDQ1) is 290 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDQ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDQ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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