Synaptotagmin-like protein 5 (SYTL5)
Homo sapiens — UniProt Q8TDW5
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-like protein 5 (SYTL5) is a protein from Homo sapiens identified by UniProt accession Q8TDW5, 730 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q8TDW5; gene symbol SYTL5.
- Organism: Homo sapiens.
- Length: 730 amino acids.
- Top disease associations (Open Targets): Trichiasis, entropion and Hernia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-like protein 5 |
|---|---|
| UniProt accession | Q8TDW5 |
| Gene | SYTL5 |
| Organism | Homo sapiens |
| Length | 730 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- Trichiasis · score 0.26
- entropion · score 0.26
- Hernia · score 0.23
- Inguinal hernia · score 0.22
- vein disorder · score 0.22
- lymphatic system disease · score 0.22
- Varicose veins · score 0.13
- papillary thyroid carcinoma · score 0.04
- pancreatic adenocarcinoma · score 0.04
- hepatocellular carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDW5-F1 | alphafold | PREDICTED | 64.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDW5.
Amino-acid sequence (730 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYTL5?
The strongest Open Targets associations for SYTL5 are Trichiasis, entropion, Hernia, Inguinal hernia and vein disorder.
How long is the SYTL5 protein?
The Homo sapiens SYTL5 protein (UniProt Q8TDW5) is 730 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDW5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDW5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.