Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1)
Homo sapiens — UniProt Q8TDX6
Data last refreshed: (UniProt release unknown)
Key facts
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1) is a protein from Homo sapiens identified by UniProt accession Q8TDX6, 532 residues long. MolForge cross-references it against 0 known binders and 231 disease associations.
- UniProt accession: Q8TDX6; gene symbol CSGALNACT1.
- Organism: Homo sapiens.
- Length: 532 amino acids.
- Top disease associations (Open Targets): skeletal dysplasia, mild, with joint laxity and advanced bone age, congenital disorder of glycosylation and Desbuquois syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
|---|---|
| UniProt accession | Q8TDX6 |
| Gene | CSGALNACT1 |
| Organism | Homo sapiens |
| Length | 532 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (231)
Diseases linked to this target (Open Targets).
- skeletal dysplasia, mild, with joint laxity and advanced bone age · score 0.74
- congenital disorder of glycosylation · score 0.46
- Desbuquois syndrome · score 0.38
- neurofibrillary tangles measurement · score 0.31
- body height · score 0.30
- self reported educational attainment · score 0.30
- hair colour measurement · score 0.29
- appendicular lean mass · score 0.29
- neutrophil count · score 0.28
- bipolar disorder · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDX6-F1 | alphafold | PREDICTED | 87.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDX6.
Amino-acid sequence (532 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CSGALNACT1?
The strongest Open Targets associations for CSGALNACT1 are skeletal dysplasia, mild, with joint laxity and advanced bone age, congenital disorder of glycosylation, Desbuquois syndrome, neurofibrillary tangles measurement and body height.
How long is the CSGALNACT1 protein?
The Homo sapiens CSGALNACT1 protein (UniProt Q8TDX6) is 532 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDX6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDX6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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