Serine/threonine-protein kinase Nek7 (NEK7)
Homo sapiens — UniProt Q8TDX7
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase Nek7 (NEK7) is a protein from Homo sapiens identified by UniProt accession Q8TDX7, 302 residues long. MolForge cross-references it against 5 known binders and 165 disease associations.
- UniProt accession: Q8TDX7; gene symbol NEK7.
- Organism: Homo sapiens.
- Length: 302 amino acids.
- Top disease associations (Open Targets): C-reactive protein measurement, neurodegenerative disease and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase Nek7 |
|---|---|
| UniProt accession | Q8TDX7 |
| Gene | NEK7 |
| Organism | Homo sapiens |
| Length | 302 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (165)
Diseases linked to this target (Open Targets).
- C-reactive protein measurement · score 0.37
- neurodegenerative disease · score 0.34
- body height · score 0.31
- heel bone mineral density · score 0.29
- Varicose veins · score 0.27
- lymphatic system disease · score 0.27
- vein disorder · score 0.27
- lateral epicondylitis · score 0.27
- high altitude adaptation · score 0.27
- breast milk measurement · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDX7-F1 | alphafold | PREDICTED | 87.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDX7.
Amino-acid sequence (302 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NEK7?
The strongest Open Targets associations for NEK7 are C-reactive protein measurement, neurodegenerative disease, body height, heel bone mineral density and Varicose veins.
How long is the NEK7 protein?
The Homo sapiens NEK7 protein (UniProt Q8TDX7) is 302 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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