Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (ASAP3)
Homo sapiens — UniProt Q8TDY4
Data last refreshed: (UniProt release unknown)
Key facts
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (ASAP3) is a protein from Homo sapiens identified by UniProt accession Q8TDY4, 903 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.
- UniProt accession: Q8TDY4; gene symbol ASAP3.
- Organism: Homo sapiens.
- Length: 903 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum gamma-glutamyl transferase measurement and calcium measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 |
|---|---|
| UniProt accession | Q8TDY4 |
| Gene | ASAP3 |
| Organism | Homo sapiens |
| Length | 903 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (94)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.40
- serum gamma-glutamyl transferase measurement · score 0.35
- calcium measurement · score 0.32
- eosinophil count · score 0.29
- triglyceride measurement · score 0.25
- serum albumin measurement · score 0.25
- total cholesterol measurement · score 0.19
- sex hormone-binding globulin measurement · score 0.19
- apolipoprotein A 1 measurement · score 0.16
- IGF-1 measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDY4-F1 | alphafold | PREDICTED | 73.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDY4.
Amino-acid sequence (903 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASAP3?
The strongest Open Targets associations for ASAP3 are neurodegenerative disease, serum gamma-glutamyl transferase measurement, calcium measurement, eosinophil count and triglyceride measurement.
How long is the ASAP3 protein?
The Homo sapiens ASAP3 protein (UniProt Q8TDY4) is 903 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDY4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDY4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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