Immunoglobulin superfamily DCC subclass member 4 (IGDCC4)
Homo sapiens — UniProt Q8TDY8
Data last refreshed: (UniProt release unknown)
Key facts
Immunoglobulin superfamily DCC subclass member 4 (IGDCC4) is a protein from Homo sapiens identified by UniProt accession Q8TDY8, 1250 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q8TDY8; gene symbol IGDCC4.
- Organism: Homo sapiens.
- Length: 1250 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, neutrophil count and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Immunoglobulin superfamily DCC subclass member 4 |
|---|---|
| UniProt accession | Q8TDY8 |
| Gene | IGDCC4 |
| Organism | Homo sapiens |
| Length | 1250 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.25
- neutrophil count · score 0.21
- mean corpuscular volume · score 0.21
- mean corpuscular hemoglobin · score 0.17
- red blood cell density measurement · score 0.12
- mean corpuscular hemoglobin concentration · score 0.11
- body height · score 0.11
- ferritin measurement · score 0.08
- neurofibrillary tangles measurement · score 0.08
- erythrocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TDY8-F1 | alphafold | PREDICTED | 70.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TDY8.
Amino-acid sequence (1250 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGDCC4?
The strongest Open Targets associations for IGDCC4 are heel bone mineral density, neutrophil count, mean corpuscular volume, mean corpuscular hemoglobin and red blood cell density measurement.
How long is the IGDCC4 protein?
The Homo sapiens IGDCC4 protein (UniProt Q8TDY8) is 1250 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TDY8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TDY8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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