OTU domain-containing protein 7A (OTUD7A)
Homo sapiens — UniProt Q8TE49
Data last refreshed: (UniProt release unknown)
Key facts
OTU domain-containing protein 7A (OTUD7A) is a protein from Homo sapiens identified by UniProt accession Q8TE49, 926 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q8TE49; gene symbol OTUD7A.
- Organism: Homo sapiens.
- Length: 926 amino acids.
- Top disease associations (Open Targets): developmental and epileptic encephalopathy, body mass index and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | OTU domain-containing protein 7A |
|---|---|
| UniProt accession | Q8TE49 |
| Gene | OTUD7A |
| Organism | Homo sapiens |
| Length | 926 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- developmental and epileptic encephalopathy · score 0.46
- body mass index · score 0.40
- Intellectual disability · score 0.37
- neurodegenerative disease · score 0.36
- Epileptic encephalopathy · score 0.34
- language impairment · score 0.34
- Severe global developmental delay · score 0.34
- Specific learning disability · score 0.34
- non-syndromic intellectual disability · score 0.34
- language disorder · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TE49-F1 | alphafold | PREDICTED | 64.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TE49.
Amino-acid sequence (926 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OTUD7A?
The strongest Open Targets associations for OTUD7A are developmental and epileptic encephalopathy, body mass index, Intellectual disability, neurodegenerative disease and Epileptic encephalopathy.
How long is the OTUD7A protein?
The Homo sapiens OTUD7A protein (UniProt Q8TE49) is 926 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TE49 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TE49 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.