D-aminoacyl-tRNA deacylase 1 (DTD1)
Homo sapiens — UniProt Q8TEA8
Data last refreshed: (UniProt release unknown)
Key facts
D-aminoacyl-tRNA deacylase 1 (DTD1) is a protein from Homo sapiens identified by UniProt accession Q8TEA8, 209 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q8TEA8; gene symbol DTD1.
- Organism: Homo sapiens.
- Length: 209 amino acids.
- Top disease associations (Open Targets): alcohol consumption measurement, feeling tense measurement and alcohol use disorder measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | D-aminoacyl-tRNA deacylase 1 |
|---|---|
| UniProt accession | Q8TEA8 |
| Gene | DTD1 |
| Organism | Homo sapiens |
| Length | 209 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- alcohol consumption measurement · score 0.33
- feeling tense measurement · score 0.26
- alcohol use disorder measurement · score 0.24
- worry measurement · score 0.21
- Abnormality of refraction · score 0.13
- age at first facial hair · score 0.10
- DNA methylation · score 0.04
- musculoskeletal system disease · score 0.04
- connective tissue disease · score 0.04
- hemoglobin measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TEA8-F1 | alphafold | PREDICTED | 85.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TEA8.
Amino-acid sequence (209 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DTD1?
The strongest Open Targets associations for DTD1 are alcohol consumption measurement, feeling tense measurement, alcohol use disorder measurement, worry measurement and Abnormality of refraction.
How long is the DTD1 protein?
The Homo sapiens DTD1 protein (UniProt Q8TEA8) is 209 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TEA8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TEA8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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