Rhomboid-related protein 4 (RHBDD1)
Homo sapiens — UniProt Q8TEB9
Data last refreshed: (UniProt release unknown)
Key facts
Rhomboid-related protein 4 (RHBDD1) is a protein from Homo sapiens identified by UniProt accession Q8TEB9, 315 residues long. MolForge cross-references it against 0 known binders and 91 disease associations.
- UniProt accession: Q8TEB9; gene symbol RHBDD1.
- Organism: Homo sapiens.
- Length: 315 amino acids.
- Top disease associations (Open Targets): electrocardiography, vital capacity and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rhomboid-related protein 4 |
|---|---|
| UniProt accession | Q8TEB9 |
| Gene | RHBDD1 |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.32
- vital capacity · score 0.30
- body height · score 0.29
- menstrual cycle measurement · score 0.22
- systolic blood pressure · score 0.20
- cytokine measurement · score 0.20
- response to vaccine · score 0.20
- lymphocyte count · score 0.19
- platelet count · score 0.19
- monocyte count · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TEB9-F1 | alphafold | PREDICTED | 79.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TEB9.
Amino-acid sequence (315 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RHBDD1?
The strongest Open Targets associations for RHBDD1 are electrocardiography, vital capacity, body height, menstrual cycle measurement and systolic blood pressure.
How long is the RHBDD1 protein?
The Homo sapiens RHBDD1 protein (UniProt Q8TEB9) is 315 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TEB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TEB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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