WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 (WFIKKN2)
Homo sapiens — UniProt Q8TEU8
Data last refreshed: (UniProt release unknown)
Key facts
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 (WFIKKN2) is a protein from Homo sapiens identified by UniProt accession Q8TEU8, 576 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.
- UniProt accession: Q8TEU8; gene symbol WFIKKN2.
- Organism: Homo sapiens.
- Length: 576 amino acids.
- Top disease associations (Open Targets): blood protein measurement, protein measurement and WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 |
|---|---|
| UniProt accession | Q8TEU8 |
| Gene | WFIKKN2 |
| Organism | Homo sapiens |
| Length | 576 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (23)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.39
- protein measurement · score 0.32
- WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 measurement · score 0.27
- cerebrospinal fluid biomarker measurement · score 0.26
- neurodegenerative disease · score 0.16
- body weight · score 0.06
- osteoarthritis, hip · score 0.06
- congenital diaphragmatic hernia · score 0.05
- spinal muscular atrophy, facioscapulohumeral type · score 0.04
- diaphragmatic hernia 3 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TEU8-F1 | alphafold | PREDICTED | 76.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TEU8.
Amino-acid sequence (576 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WFIKKN2?
The strongest Open Targets associations for WFIKKN2 are blood protein measurement, protein measurement, WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 measurement, cerebrospinal fluid biomarker measurement and neurodegenerative disease.
How long is the WFIKKN2 protein?
The Homo sapiens WFIKKN2 protein (UniProt Q8TEU8) is 576 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TEU8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TEU8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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