Cyclic AMP-responsive element-binding protein 3-like protein 4 (CREB3L4)
Homo sapiens — UniProt Q8TEY5
Data last refreshed: (UniProt release unknown)
Key facts
Cyclic AMP-responsive element-binding protein 3-like protein 4 (CREB3L4) is a protein from Homo sapiens identified by UniProt accession Q8TEY5, 395 residues long. MolForge cross-references it against 0 known binders and 156 disease associations.
- UniProt accession: Q8TEY5; gene symbol CREB3L4.
- Organism: Homo sapiens.
- Length: 395 amino acids.
- Top disease associations (Open Targets): blood protein measurement, total blood protein measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
|---|---|
| UniProt accession | Q8TEY5 |
| Gene | CREB3L4 |
| Organism | Homo sapiens |
| Length | 395 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (156)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.17
- total blood protein measurement · score 0.11
- mathematical ability · score 0.11
- neuroimaging measurement · score 0.11
- balding measurement · score 0.10
- self reported educational attainment · score 0.10
- brain volume measurement · score 0.10
- prostate carcinoma · score 0.10
- azoospermia · score 0.09
- diet measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TEY5-F1 | alphafold | PREDICTED | 60.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TEY5.
Amino-acid sequence (395 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CREB3L4?
The strongest Open Targets associations for CREB3L4 are blood protein measurement, total blood protein measurement, mathematical ability, neuroimaging measurement and balding measurement.
How long is the CREB3L4 protein?
The Homo sapiens CREB3L4 protein (UniProt Q8TEY5) is 395 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TEY5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TEY5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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