Ubiquitin carboxyl-terminal hydrolase 33 (USP33)
Homo sapiens — UniProt Q8TEY7
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin carboxyl-terminal hydrolase 33 (USP33) is a protein from Homo sapiens identified by UniProt accession Q8TEY7, 942 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q8TEY7; gene symbol USP33.
- Organism: Homo sapiens.
- Length: 942 amino acids.
- Top disease associations (Open Targets): ovarian cancer, breast adenocarcinoma and vital capacity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin carboxyl-terminal hydrolase 33 |
|---|---|
| UniProt accession | Q8TEY7 |
| Gene | USP33 |
| Organism | Homo sapiens |
| Length | 942 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.23
- breast adenocarcinoma · score 0.23
- vital capacity · score 0.19
- body mass index · score 0.14
- physical activity measurement · score 0.14
- forced expiratory volume · score 0.10
- peak expiratory flow · score 0.09
- obesity · score 0.09
- hip circumference · score 0.09
- gonorrhea · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8TEY7-F1 | alphafold | PREDICTED | 70.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TEY7.
Amino-acid sequence (942 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with USP33?
The strongest Open Targets associations for USP33 are ovarian cancer, breast adenocarcinoma, vital capacity, body mass index and physical activity measurement.
How long is the USP33 protein?
The Homo sapiens USP33 protein (UniProt Q8TEY7) is 942 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8TEY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8TEY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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