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Ankyrin repeat domain-containing protein 24 (ANKRD24)

Homo sapiens — UniProt Q8TF21

Gene: ANKRD24Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ankyrin repeat domain-containing protein 24 (ANKRD24) is a protein from Homo sapiens identified by UniProt accession Q8TF21, 1146 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

  • UniProt accession: Q8TF21; gene symbol ANKRD24.
  • Organism: Homo sapiens.
  • Length: 1146 amino acids.
  • Top disease associations (Open Targets): blood phosphate measurement, mean corpuscular hemoglobin and body height.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAnkyrin repeat domain-containing protein 24
UniProt accessionQ8TF21
GeneANKRD24
OrganismHomo sapiens
Length1146 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (10)

Diseases linked to this target (Open Targets).

  • blood phosphate measurement · score 0.25
  • mean corpuscular hemoglobin · score 0.19
  • body height · score 0.09
  • benign adult familial myoclonic epilepsy · score 0.06
  • deafness · score 0.05
  • rolandic epilepsy-paroxysmal exercise-induced dystonia-writer's cramp syndrome · score 0.04
  • COVID-19 · score 0.01
  • spinocerebellar ataxia type 17 · score 0.00
  • neoplasm · score 0.00
  • metopic craniosynostosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8TF21-F1alphafoldPREDICTED69.40—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8TF21.

Amino-acid sequence (1146 residues)

MKTLRARFKK TELRLSPTDL GSCPPCGPCP IPKPAARGRR QSQDWGKSDE RLLQAVENND APRVAALIAR KGLVPTKLDP EGKSAFHLAA MRGAASCLEV MIAHGSNVMS ADGAGYNALH LAAKYGHPQC LKQLLQASCV VDVVDSSGWT ALHHAAAGGC LSCSEVLCSF KAHLNPQDRS GATPLIIAAQ MCHTDLCRLL LQQGAAANDQ DLQGRTALML ACEGASPETV EVLLQGGAQP GITDALGQDA AHYGALAGDK LILHLLQEAA QRPSPPSALT EDDSGEASSQ NSMSSHGKQG APKKRKAPPP PASIPMPDDR DAYEEIVRLR QERGRLLQKI RGLEQHKERR QQESPEASSL HILERQVQEL QQLLVERQEE KESLGREVES LQSRLSLLEN ERENTSYDVT TLQDEEGELP DLPGAEVLLS RQLSPSAQEH LASLQEQVAV LTRQNQELME KVQILENFEK DETQMEVEAL AEVIPLALYD SLRAEFDQLR RQHAEALQAL RQQETREVPR EEGAACGESE VAGATATKNG PTHMELNGSV APETKVNGAE TIDEEAAGDE TMEARTMEAE ATGAEATGAE ATGAKVTETK PTGAEVREME TTEEEANMET KPTGAQATDT ETTGVEAMGV EATKTKAEEA EMQAYGVGAG QAEPPVTGTT NMEATGSRAT GMESTGVSAT GVENPGVEAT VPGISAGPIL HPGAAEASEK LQVELETRIR GLEEALRQRE REAAAELEAA LGKCEAAEAE AGRLRERVRE AEGSGASGGG GGDTTQLRAA LEQAREDLRD RDSRLRELEA ASACLDEARA SRLLAEEEAR GLRAELAQRE EARLEQSREL EVLREQLATA RATGEQQRTA AAELGRARDA AEARVAELPA ACEEARQGLA ELREASEALR QSVVPASEHR RLQEEALELR GRAASLEQEV VATGKEAARL RAELERERVC SVALSEHERI VGTLQANVAQ LEGQLEELGR RHEKTSAEVF QVQREALFMK SERHAAEAQL ATAEQQLRGL RTEAERARQA QSRAQEALDK AKEKDKKITE LSKEVFNLKE ALKEQPAALA TPEVEALRDQ VKDLQQQLQE AARDHSSVVA LYRSHLLYAI QGQMDEDVQR ILSQILQMQR LQAQGR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ANKRD24?

The strongest Open Targets associations for ANKRD24 are blood phosphate measurement, mean corpuscular hemoglobin, body height, benign adult familial myoclonic epilepsy and deafness.

How long is the ANKRD24 protein?

The Homo sapiens ANKRD24 protein (UniProt Q8TF21) is 1146 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8TF21
GeneANKRD24
OrganismHomo sapiens
Length1146
Binders0
Diseases10
View on UniProt