Glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5)
Homo sapiens — UniProt Q8WTR4
Data last refreshed: (UniProt release unknown)
Key facts
Glycerophosphodiester phosphodiesterase domain-containing protein 5 (GDPD5) is a protein from Homo sapiens identified by UniProt accession Q8WTR4, 605 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q8WTR4; gene symbol GDPD5.
- Organism: Homo sapiens.
- Length: 605 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, breast adenocarcinoma and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycerophosphodiester phosphodiesterase domain-containing protein 5 |
|---|---|
| UniProt accession | Q8WTR4 |
| Gene | GDPD5 |
| Organism | Homo sapiens |
| Length | 605 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.23
- body height · score 0.21
- coronary artery disease · score 0.20
- head and neck squamous cell carcinoma · score 0.11
- axial length measurement · score 0.07
- metabolite measurement · score 0.06
- amyotrophic lateral sclerosis · score 0.04
- neuronal ceroid lipofuscinosis 1 · score 0.04
- hyperpigmentation with or without hypopigmentation, familial progressive · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WTR4-F1 | alphafold | PREDICTED | 86.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WTR4.
Amino-acid sequence (605 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GDPD5?
The strongest Open Targets associations for GDPD5 are glioblastoma multiforme, breast adenocarcinoma, body height, coronary artery disease and head and neck squamous cell carcinoma.
How long is the GDPD5 protein?
The Homo sapiens GDPD5 protein (UniProt Q8WTR4) is 605 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WTR4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WTR4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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