Palmitoyltransferase ZDHHC1 (ZDHHC1)
Homo sapiens — UniProt Q8WTX9
Data last refreshed: (UniProt release unknown)
Key facts
Palmitoyltransferase ZDHHC1 (ZDHHC1) is a protein from Homo sapiens identified by UniProt accession Q8WTX9, 485 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q8WTX9; gene symbol ZDHHC1.
- Organism: Homo sapiens.
- Length: 485 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean platelet volume and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Palmitoyltransferase ZDHHC1 |
|---|---|
| UniProt accession | Q8WTX9 |
| Gene | ZDHHC1 |
| Organism | Homo sapiens |
| Length | 485 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.17
- mean platelet volume · score 0.13
- neoplasm · score 0.09
- erythrocyte count · score 0.08
- vital capacity · score 0.08
- cancer · score 0.08
- FEV/FVC ratio · score 0.06
- mean corpuscular hemoglobin concentration · score 0.05
- BMI-adjusted waist-hip ratio · score 0.04
- blood protein measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WTX9-F1 | alphafold | PREDICTED | 67.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WTX9.
Amino-acid sequence (485 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZDHHC1?
The strongest Open Targets associations for ZDHHC1 are mean corpuscular volume, mean platelet volume, neoplasm, erythrocyte count and vital capacity.
How long is the ZDHHC1 protein?
The Homo sapiens ZDHHC1 protein (UniProt Q8WTX9) is 485 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WTX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WTX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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