Glycine N-acyltransferase-like protein 2 (GLYATL2)

About Glycine N-acyltransferase-like protein 2

Glycine N-acyltransferase-like protein 2 (GLYATL2) is a protein from Homo sapiens identified by UniProt accession Q8WU03, 294 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Glycine N-acyltransferase-like protein 2
UniProt accession	Q8WU03
Gene	GLYATL2
Organism	Homo sapiens
Length	294 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
heart failure · score 0.30
hypertrophic cardiomyopathy · score 0.30
cutaneous melanoma · score 0.26
lung adenocarcinoma · score 0.26
glioblastoma multiforme · score 0.16
squamous cell lung carcinoma · score 0.15
head and neck squamous cell carcinoma · score 0.15
lean body mass · score 0.06
non-small cell lung carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8WU03-F1	alphafold	PREDICTED	89.82	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WU03.

Amino-acid sequence (294 residues)

MLVLHNSQKL QILYKSLEKS IPESIKVYGA IFNIKDKNPF NMEVLVDAWP DYQIVITRPQ KQEMKDDQDH YTNTYHIFTK APDKLEEVLS YSNVISWEQT LQIQGCQEGL DEAIRKVATS KSVQVDYMKT ILFIPELPKK HKTSSNDKME LFEVDDDNKE GNFSNMFLDA SHAGLVNEHW AFGKNERSLK YIERCLQDFL GFGVLGPEGQ LVSWIVMEQS CELRMGYTVP KYRHQGNMLQ IGYHLEKYLS QKEIPFYFHV ADNNEKSLQA LNNLGFKICP CGWHQWKCTP KKYC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards