Glycine N-acyltransferase-like protein 2 (GLYATL2)
Homo sapiens — UniProt Q8WU03
Data last refreshed: (UniProt release unknown)
Key facts
Glycine N-acyltransferase-like protein 2 (GLYATL2) is a protein from Homo sapiens identified by UniProt accession Q8WU03, 294 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q8WU03; gene symbol GLYATL2.
- Organism: Homo sapiens.
- Length: 294 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, heart failure and hypertrophic cardiomyopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycine N-acyltransferase-like protein 2 |
|---|---|
| UniProt accession | Q8WU03 |
| Gene | GLYATL2 |
| Organism | Homo sapiens |
| Length | 294 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- heart failure · score 0.30
- hypertrophic cardiomyopathy · score 0.30
- cutaneous melanoma · score 0.26
- lung adenocarcinoma · score 0.26
- glioblastoma multiforme · score 0.16
- squamous cell lung carcinoma · score 0.15
- head and neck squamous cell carcinoma · score 0.15
- lean body mass · score 0.06
- non-small cell lung carcinoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WU03-F1 | alphafold | PREDICTED | 89.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WU03.
Amino-acid sequence (294 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLYATL2?
The strongest Open Targets associations for GLYATL2 are neurodegenerative disease, heart failure, hypertrophic cardiomyopathy, cutaneous melanoma and lung adenocarcinoma.
How long is the GLYATL2 protein?
The Homo sapiens GLYATL2 protein (UniProt Q8WU03) is 294 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WU03 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WU03 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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