Uncharacterized protein C2orf15 (C2orf15)
Homo sapiens — UniProt Q8WU43
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C2orf15 (C2orf15) is a protein from Homo sapiens identified by UniProt accession Q8WU43, 91 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q8WU43; gene symbol C2orf15.
- Organism: Homo sapiens.
- Length: 91 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, FEV/FVC ratio and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C2orf15 |
|---|---|
| UniProt accession | Q8WU43 |
| Gene | C2orf15 |
| Organism | Homo sapiens |
| Length | 91 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- FEV/FVC ratio · score 0.05
- lysosomal storage disease · score 0.05
- colorectal adenocarcinoma · score 0.04
- reticulocyte count · score 0.03
- reticulocyte measurement · score 0.03
- Obesity · score 0.00
- type 2 diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WU43-F1 | alphafold | PREDICTED | 58.25 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WU43.
Amino-acid sequence (91 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C2orf15?
The strongest Open Targets associations for C2orf15 are neurodegenerative disease, FEV/FVC ratio, lysosomal storage disease, colorectal adenocarcinoma and reticulocyte count.
How long is the C2orf15 protein?
The Homo sapiens C2orf15 protein (UniProt Q8WU43) is 91 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WU43 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WU43 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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