Peptidyl-prolyl cis-trans isomerase-like 4 (PPIL4)
Homo sapiens — UniProt Q8WUA2
Data last refreshed: (UniProt release unknown)
Key facts
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIL4) is a protein from Homo sapiens identified by UniProt accession Q8WUA2, 492 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q8WUA2; gene symbol PPIL4.
- Organism: Homo sapiens.
- Length: 492 amino acids.
- Top disease associations (Open Targets): lymphocyte count, blood protein measurement and response to antidepressant.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase-like 4 |
|---|---|
| UniProt accession | Q8WUA2 |
| Gene | PPIL4 |
| Organism | Homo sapiens |
| Length | 492 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.04
- blood protein measurement · score 0.04
- response to antidepressant · score 0.04
- atrial fibrillation · score 0.04
- atrial flutter · score 0.03
- peak expiratory flow · score 0.02
- brain aneurysm · score 0.01
- viral disease · score 0.00
- Hao-Fountain syndrome · score 0.00
- Neurodevelopmental disorder · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUA2-F1 | alphafold | PREDICTED | 70.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUA2.
Amino-acid sequence (492 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPIL4?
The strongest Open Targets associations for PPIL4 are lymphocyte count, blood protein measurement, response to antidepressant, atrial fibrillation and atrial flutter.
How long is the PPIL4 protein?
The Homo sapiens PPIL4 protein (UniProt Q8WUA2) is 492 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUA2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUA2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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