Tsukushi (TSKU)
Homo sapiens — UniProt Q8WUA8
Data last refreshed: (UniProt release unknown)
Key facts
Tsukushi (TSKU) is a protein from Homo sapiens identified by UniProt accession Q8WUA8, 353 residues long. MolForge cross-references it against 0 known binders and 141 disease associations.
- UniProt accession: Q8WUA8; gene symbol TSKU.
- Organism: Homo sapiens.
- Length: 353 amino acids.
- Top disease associations (Open Targets): body mass index, vitamin D measurement and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tsukushi |
|---|---|
| UniProt accession | Q8WUA8 |
| Gene | TSKU |
| Organism | Homo sapiens |
| Length | 353 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (141)
Diseases linked to this target (Open Targets).
- body mass index · score 0.49
- vitamin D measurement · score 0.45
- body fat percentage · score 0.42
- self reported educational attainment · score 0.41
- factor VII measurement · score 0.40
- lean body mass · score 0.35
- gastroesophageal reflux disease · score 0.33
- type 2 diabetes mellitus · score 0.33
- cognitive function measurement · score 0.32
- endometriosis · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUA8-F1 | alphafold | PREDICTED | 86.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUA8.
Amino-acid sequence (353 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSKU?
The strongest Open Targets associations for TSKU are body mass index, vitamin D measurement, body fat percentage, self reported educational attainment and factor VII measurement.
How long is the TSKU protein?
The Homo sapiens TSKU protein (UniProt Q8WUA8) is 353 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUA8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUA8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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