PHD finger protein 10 (PHF10)
Homo sapiens — UniProt Q8WUB8
Data last refreshed: (UniProt release unknown)
Key facts
PHD finger protein 10 (PHF10) is a protein from Homo sapiens identified by UniProt accession Q8WUB8, 498 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q8WUB8; gene symbol PHF10.
- Organism: Homo sapiens.
- Length: 498 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, smoking status measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PHD finger protein 10 |
|---|---|
| UniProt accession | Q8WUB8 |
| Gene | PHF10 |
| Organism | Homo sapiens |
| Length | 498 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- smoking status measurement · score 0.13
- self reported educational attainment · score 0.13
- gonorrhea · score 0.08
- eye morphology measurement · score 0.07
- antisocial behaviour measurement · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- substance abuse · score 0.06
- cancer · score 0.06
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUB8-F1 | alphafold | PREDICTED | 70.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUB8.
Amino-acid sequence (498 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PHF10?
The strongest Open Targets associations for PHF10 are neurodegenerative disease, smoking status measurement, self reported educational attainment, gonorrhea and eye morphology measurement.
How long is the PHF10 protein?
The Homo sapiens PHF10 protein (UniProt Q8WUB8) is 498 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUB8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUB8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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