RelA-associated inhibitor (PPP1R13L)
Homo sapiens — UniProt Q8WUF5
Data last refreshed: (UniProt release unknown)
Key facts
RelA-associated inhibitor (PPP1R13L) is a protein from Homo sapiens identified by UniProt accession Q8WUF5, 828 residues long. MolForge cross-references it against 0 known binders and 401 disease associations.
- UniProt accession: Q8WUF5; gene symbol PPP1R13L.
- Organism: Homo sapiens.
- Length: 828 amino acids.
- Top disease associations (Open Targets): dilated cardiomyopathy, Microcephaly - facio-cardio-skeletal syndrome, Hadziselimovic type and sudden cardiac arrest.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RelA-associated inhibitor |
|---|---|
| UniProt accession | Q8WUF5 |
| Gene | PPP1R13L |
| Organism | Homo sapiens |
| Length | 828 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (401)
Diseases linked to this target (Open Targets).
- dilated cardiomyopathy · score 0.57
- Microcephaly - facio-cardio-skeletal syndrome, Hadziselimovic type · score 0.45
- sudden cardiac arrest · score 0.38
- Dilated cardiomyopathy · score 0.37
- cardiac conduction defect · score 0.37
- orofacial cleft · score 0.34
- multiple congenital anomalies/dysmorphic syndrome · score 0.34
- Orofacial cleft · score 0.34
- breast adenocarcinoma · score 0.25
- head and neck squamous cell carcinoma · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUF5-F1 | alphafold | PREDICTED | 57.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUF5.
Amino-acid sequence (828 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R13L?
The strongest Open Targets associations for PPP1R13L are dilated cardiomyopathy, Microcephaly - facio-cardio-skeletal syndrome, Hadziselimovic type, sudden cardiac arrest, Dilated cardiomyopathy and cardiac conduction defect.
How long is the PPP1R13L protein?
The Homo sapiens PPP1R13L protein (UniProt Q8WUF5) is 828 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUF5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUF5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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