Cotranscriptional regulator ARB2A (ARB2A)
Homo sapiens — UniProt Q8WUF8
Data last refreshed: (UniProt release unknown)
Key facts
Cotranscriptional regulator ARB2A (ARB2A) is a protein from Homo sapiens identified by UniProt accession Q8WUF8, 416 residues long. MolForge cross-references it against 0 known binders and 225 disease associations.
- UniProt accession: Q8WUF8; gene symbol ARB2A.
- Organism: Homo sapiens.
- Length: 416 amino acids.
- Top disease associations (Open Targets): cortical surface area measurement, neuroimaging measurement and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cotranscriptional regulator ARB2A |
|---|---|
| UniProt accession | Q8WUF8 |
| Gene | ARB2A |
| Organism | Homo sapiens |
| Length | 416 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (225)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.45
- neuroimaging measurement · score 0.35
- diet measurement · score 0.34
- brain measurement · score 0.31
- unipolar depression · score 0.26
- neuroticism measurement · score 0.25
- bone density · score 0.25
- urate measurement · score 0.25
- self reported educational attainment · score 0.23
- hemorrhoid · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUF8-F1 | alphafold | PREDICTED | 84.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUF8.
Amino-acid sequence (416 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARB2A?
The strongest Open Targets associations for ARB2A are cortical surface area measurement, neuroimaging measurement, diet measurement, brain measurement and unipolar depression.
How long is the ARB2A protein?
The Homo sapiens ARB2A protein (UniProt Q8WUF8) is 416 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUF8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUF8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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