Protein Churchill (CHURC1)
Homo sapiens — UniProt Q8WUH1
Data last refreshed: (UniProt release unknown)
Key facts
Protein Churchill (CHURC1) is a protein from Homo sapiens identified by UniProt accession Q8WUH1, 112 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.
- UniProt accession: Q8WUH1; gene symbol CHURC1.
- Organism: Homo sapiens.
- Length: 112 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean reticulocyte volume and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein Churchill |
|---|---|
| UniProt accession | Q8WUH1 |
| Gene | CHURC1 |
| Organism | Homo sapiens |
| Length | 112 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (33)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.24
- mean reticulocyte volume · score 0.18
- reticulocyte count · score 0.12
- testosterone measurement · score 0.09
- Red cell distribution width · score 0.08
- lean body mass · score 0.07
- bilirubin measurement · score 0.07
- reticulocyte measurement · score 0.07
- mean corpuscular hemoglobin concentration · score 0.07
- hair colour measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUH1-F1 | alphafold | PREDICTED | 93.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUH1.
Amino-acid sequence (112 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHURC1?
The strongest Open Targets associations for CHURC1 are mean corpuscular volume, mean reticulocyte volume, reticulocyte count, testosterone measurement and Red cell distribution width.
How long is the CHURC1 protein?
The Homo sapiens CHURC1 protein (UniProt Q8WUH1) is 112 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUH1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUH1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.