Transmembrane protein 263 (TMEM263)
Homo sapiens — UniProt Q8WUH6
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 263 (TMEM263) is a protein from Homo sapiens identified by UniProt accession Q8WUH6, 116 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.
- UniProt accession: Q8WUH6; gene symbol TMEM263.
- Organism: Homo sapiens.
- Length: 116 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, body height and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 263 |
|---|---|
| UniProt accession | Q8WUH6 |
| Gene | TMEM263 |
| Organism | Homo sapiens |
| Length | 116 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (46)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.43
- body height · score 0.38
- bone density · score 0.37
- lean body mass · score 0.36
- heel bone mineral density · score 0.35
- influenza A (H1N1) · score 0.28
- femoral neck bone mineral density · score 0.28
- blood phosphate measurement · score 0.26
- base metabolic rate measurement · score 0.25
- fat body mass · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8WUH6-F1 | alphafold | PREDICTED | 51.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8WUH6.
Amino-acid sequence (116 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM263?
The strongest Open Targets associations for TMEM263 are alkaline phosphatase measurement, body height, bone density, lean body mass and heel bone mineral density.
How long is the TMEM263 protein?
The Homo sapiens TMEM263 protein (UniProt Q8WUH6) is 116 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8WUH6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8WUH6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.